Moorfields Eye Hospital

Mr Lyndon da Cruz

I am a Consultant vitreoretinal Surgeon and medical retinal specialist at Moorfields Eye Hospital.  As Clinical lead for the London Project I will co-ordinate and operate for the programme of pre-clinical transplantation experiments for safety and efficacy stem cells and clinical phase trials.  In tandem I will carry out the autologous -RPE transplantation  trials for inherited macular dystrophies and Dry Age-related Macular Degeneration (AMD).  My main research interest is in the field of therapies for blinding retinal conditions such as AMD.

Key achievements

Lyndon da Cruz completed his medical studies in Perth, Western Australia. He began his research interest in retinal disease at the Nuffield Laboratory of Ophthalmology, in Oxford in 1990. On completion of the English surgical fellowship he returned to Australia to carry out a PhD at the Lions Eye Institute, Perth Australia. He completed his Australian speciality training and carried out a vitreo-retinal surgical fellowship  with Ian McAllister in Perth.  He was awarded the NH and MRC post-doctoral fellowship in 1999 and named the Menzies Scholar in Science and Medicine for Australia in 2000. The latter awarded to the highest ranked postdoctoral fellow in Australia in medicine and science. He won the Howard Florey Post-doctoral Fellowship from the Royal Society that brought him to London to study with Prof. Alan Bird. He finished his clinical training with further vitreoretinal surgical fellowships in London, at Moorfields Eye Hospital.

Key publications

• da Cruz L, Chen F, Ahmado A, Greenwood J, Coffey P.  RPE transplantation and its role in retinal disease. Prog Retin Eye Res. 2007 Nov;26(6):598-635. Epub 2007 Jul 25.
• Uppal G, Milliken A, Lee J, Acheson J, Hykin P, Tufail A, da Cruz L.  New algorithm for assessing patient suitability for macular translocation surgery. Clin Experiment Ophthalmol. 2007 Jul;35(5):448-57.
• Vugler A, Lawrence J, Walsh J, Carr A, Gias C, Semo M, Ahmado A, da Cruz L, Andrews P, Coffey P.  Embryonic stem cells and retinal repair. Mech Dev. 2007 Aug 15.
• RE MacLaren GS Uppal, KS Balaggan, AD Tufail, PM Munro, AB Milliken, RR Ali, GS Rubin, GW Aylward, L Da Cruz.  Autologous transplantation of the retinal pigment epithelium in the treatment of neovascular age-related macular degeneration.., Ophthalmology. 2007 Mar;114(3):561-70.
• Abeysiri P, Bunce C, da Cruz L. Outcomes of surgery for retinal detachment in patients with Stickler syndrome: a comparison of two sequential 20-year cohorts. Graefes Arch Clin Exp Ophthalmol. 2007 Jun 20;

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